Summers mean a lot of out-door time. Viana offers a range of high performance color cosmetics and skincare products and giving careful attention to your needs. OR INTRAVAGINAL USE, doxycycline, clindamycin topical, erythromycin topical, minocycline, Tazorac. For purposes of comparisons of the animal exposure to human exposure, the recommended clinical dose is defined as 1 g of Ziana Gel applied daily to a 60 kg person. Although no definite pattern of teratogenicity and no causal association have been established from these cases, five of the reports describe the rare birth defect category, holoprosencephaly (defects associated with incomplete midline development of the forebrain). BLOG It’s light , moisturising without been oily and the night cream feels so relaxing. Putting it all together. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. for about 15 minutes or until ganache firms up a bit. Teratology (Segment II) studies using clindamycin were performed orally in rats (up to 600 mg/kg/day) and mice (up to 100 mg/kg/day) (583 and 49 times amount of clindamycin in the recommended clinical dose based on body surface area comparison, respectively) or with subcutaneous doses of clindamycin up to 180 mg/kg/day (175 and 88 times the amount of clindamycin in the recommended clinical dose based on body surface area comparison, respectively) revealed no evidence of teratogenicity. It may harm them. Stop Ziana Gel and call your doctor if your skin becomes very red, swollen, blistered, or crusted. Apply the mixture to your … The contribution of clindamycin to that effect is unknown. The chemical name for clindamycin phosphate is Methyl 7-chloro-6,7,8-trideoxy-6-(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-α-D-galacto-octopyranoside 2-(dihydrogen phosphate). (clindamycin phosphate 1.2% and tretinoin 0.025%) Gel. Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Dec 2020), ASHP (updated 3 Dec 2020) and others. Therefore, Ziana Gel should be used with caution in patients receiving such agents. Ziana Gel should not be used in combination with erythromycin-containing products due to its clindamycin component. Store Ziana Gel at room temperature, 59° to 86°F (15° to 30°C). No carcinogenicity was observed with maximum effects of dermal amyloidosis in the basal layer of the skin. You can register after completing checkout. According to the guests' opinions, waiters … Sign up for emails and receive 10% off your next purchase. 0 out of 5 ... SUN Cream … Shop Online Today! It helps decrease the number and severity of acne pimples and helps pimples that do develop to heal more quickly. If your face becomes sunburned, stop Ziana Gel until your skin has healed. One of the most effective ways to protect you from the sun is through the application of sunscreen. Laval, Quebec H7L 4A8, Canada, Ziana® The carcinogenicity of a 1% clindamycin phosphate gel similar to Ziana Gel was evaluated by daily application to mice for 2 years. Both tests were negative. ©Valeant Pharmaceuticals North America LLC, PATIENT INFORMATION Valeant Pharmaceuticals International, Inc. Bridgewater, NJ 08807 USA, By: It contains 20% glycolic acid and 10% lactic acid. The colitis is usually characterized by severe persistent diarrhea and severe abdominal cramps and may be associated with the passage of blood and mucus. Daily use of sunscreen products and protective apparel (e.g., a hat) are recommended. Do not use Ziana Gel for a condition for which it was not prescribed. Shop Viennas products online and money-saving specials with the click of a mouse. Shop Viana face creams, sun protection, acne treatments, body butters, body wash, face packs, face scrubs, & other skin treats Valeant Pharmaceuticals International, Inc. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother. Laval, Quebec H7L 4A8, Canada shop sun care Anti-Aging sunscreen products for face, neck and décolleté. Do not give Ziana Gel to other people, even if they have the same symptoms you have. In oral Segment III studies in rats with tretinoin, decreased survival of neonates and growth retardation were observed at doses in excess of 2 mg/kg/day (~78 times the recommended clinical dose assuming 100% absorption and based on body surface area comparison). Shop online for your favorite Branded Shampoo at affordable prices. UV block + brightening + anti-wrinkle effects and PA++++ protection. Use a big enough bowl because the cream will double in volume. Ziana Gel is available in 30 gram and 60 gram tubes. (Photo by Viana Boenzli) Chill in refrigerator (seeing a trend here?) This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Medicines are sometimes prescribed for purposes other than those listed in patient information leaflet. In Studies 1 and 2, 1277 subjects enrolled with moderate to severe acne, 854 subjects treated with Ziana Gel and 423 treated with vehicle. Although the exact mode of action of tretinoin is unknown, current evidence suggests that topical tretinoin decreases cohesiveness of follicular epithelial cells with decreased microcomedo formation. Ziana Gel is indicated for the topical treatment of acne vulgaris in patients 12 years or older. The safety data presented in Table 1 (below) reflects exposure to Ziana Gel in 1853 patients with acne vulgaris. Eighteen out of 442 subjects (4%) reported gastrointestinal symptoms. Plasma concentrations for clindamycin generally did not exceed 3.5 ng/mL, with the exception of one subject whose plasma concentration reached 13.1 ng/mL. Ziana Gel should be kept away from the eyes, the mouth, angles of the nose, and mucous membranes. If you would like more information, talk with your doctor. Shop Online Today! These are not all the side effects with Ziana Gel. Ziana Gel is an antibiotic and retinoid combination medicine used for the skin treatment of acne in patients 12 years and older. Fast & convenient delivery. Specially enjoyed the expansive Cabedelo beach, the cream filled doughnut-like balls (Bolas de Berlim from Jose Natário Cafe. Use the Arbutin 5% Eres Tu Serum on a regular basis to improve the brightening of the skin. Ingredients and Benefits of Cica Perfect Sun Cream:⁣⁠ ... We are working on new features to make your experience with Viana Care more convenient. Health & Beauty, Viana, Women's Health and Beauty Viana Hair Thickening & Volumizing Shampoo 275ml-CSNC3703. We comply with the HONcode standard for trustworthy health information -. When used with Ziana Gel, there may be increased skin irritation. 2syringes / 1.1ml / 4x 23G needles $ 77.00. The co-primary efficacy variables were: The EGS scoring scale used in all of the clinical trials for Ziana Gel is as follows: Normal, clear skin with no evidence of acne vulgaris, Rare non-inflammatory lesions present, with rare non-inflamed papules (papules must be resolving and may be hyperpigmented, though not pink-red), Some non-inflammatory lesions are present, with few inflammatory lesions (papules/pustules only; no nodulocystic lesions), Non-inflammatory lesions predominate, with multiple inflammatory lesions evident: several to many comedones and papules/pustules, and there may or may not be one small nodulo-cystic lesion, Inflammatory lesions are more apparent, many comedones and papules/pustules, there may or may not be a few nodulocystic lesions, Highly inflammatory lesions predominate, variable number of comedones, many papules/pustules and many nodulocystic lesions. Patients were 12 years and older and were treated once daily for 12 weeks. Weather extremes, such as wind or cold, also may be irritating to patients under treatment with Ziana Gel. Pregnancy Category C. There are no well-controlled trials in pregnant women treated with Ziana Gel. We supply CA, AZ, NV, NM, and West Texas with a wide range of … (clindamycin phosphate 1.2% With widespread use of any drug, a small number of birth defect reports associated temporally with the administration of the drug would be expected by chance alone. Shop online for your favorite Makeup Products at affordable prices. A creme légere does not have enough fat to hold the air bubbles, a richer cream will not make much volume. Talk to your doctor about any side effect that bothers you or that does not go away. Generic Name: clindamycin phosphate and tretinoin Oral tretinoin has been shown to be fetotoxic in rats when administered in doses 78 times the recommended clinical dose based on body surface area comparison. The chemical name for tretinoin is 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8 nonatetraenoic acid (all-trans form). More savings on your Viennas favourites. 2. about all the medicines and skin products you use: Do not get Ziana Gel in your eyes or mouth, on your lips, on the corners of your nose, or on open wounds. The clinical significance of this in vitro antagonism is not known. Promotion Codes. The daily doses used in this study were approximately 13 and 72 times higher than the human dose of clindamycin phosphate from Ziana Gel, assuming complete absorption and based on body surface area comparison. Inactive Ingredients: butylated hydroxytoluene NF, carbomer 981 NF, citric acid USP, edetate disodium USP, glycerin USP, methylparaben NF, polysorbate 80 NF, propylparaben NF, purified water USP and tromethamine USP. The genotoxic potential of tretinoin was evaluated in an in vitro Ames Salmonella reversion test and an in vitro chromosomal aberration assay in Chinese hamster ovary cells. Cica Perfect Sun Cream. Concomitant topical medication, medicated or abrasive soaps and cleansers, soaps and cosmetics that have a strong drying effect, and products with high concentrations of alcohol, astringents, spices or lime should be used with caution. Because many drugs are excreted in human milk, caution should be exercised when Ziana Gel is administered to a nursing woman. Stimulates the blood … Cica Perfect Sun Cream $ 21.00. Keep Ziana Gel and all medicines out of reach of children. One open-label 12-month safety study for Ziana Gel showed a similar adverse reaction profile as seen in the 12-week studies. please expect a delay in receiving shipping confirmation. Makeup; Hair Care; Brushes & Tools; DEALSSALE! Active Ingredients: clindamycin phosphate 1.2% and tretinoin 0.025%. Moisturizing kincare effect suncream with paschal candle culture extract for soothing and moisturizing the skin. Additionally, tretinoin stimulates mitotic activity and increased turnover of follicular epithelial cells causing extrusion of the comedones. In Study 3, Ziana Gel was compared to clindamycin gel in a total of 2010 patients with moderate or severe acne vulgaris (see Table 3). Last updated on Feb 20, 2020. The adverse reaction information from clinical trials does, however, provide a basis for identifying the adverse reactions that appear to be related to drug use for approximating rates. You will always receive free worldwide express shipping on orders over $500. 3. Read the Patient Information that comes with Ziana Gel before you start using it and each time you get a refill. Viana … Ziana Gel at 600 mg/kg/day (approximately 12 times the recommended clinical dose assuming 100% absorption and based on body surface area comparison) was considered to be the no-observed-adverse-effect level (NOAEL) for maternal and developmental toxicity following dermal administration of Ziana Gel for 2 weeks prior to artificial insemination and continuing until gestation day 18, inclusive. It is not known whether tretinoin is excreted in human milk. Ziana Gel is contraindicated in patients with regional enteritis, ulcerative colitis, or history of antibiotic-associated colitis. The Chaeum Premium 4. Patients who may be required to have considerable sun exposure due to occupation and those with inherent sensitivity to the sun should exercise particular caution. Donie Sun 47,698 views. Shop the My Fairness Solution for Skin that is, Hyperpigmented, Uneven, and Damaged by UV Rays for Both Face, and Body Every 4 weeks the epidermal layer of the skin has a turnover and completely renews its cells. Severe colitis has occurred following oral or parenteral administration of clindamycin with an onset of up to several weeks following cessation of therapy. Dermal tretinoin has been shown to be fetotoxic in rabbits when administered in doses 40 times the recommended human clinical dose based on body surface area comparison. There may be new information. Add to cart +Gift. Resistance to clindamycin is often associated with resistance to erythromycin. Diarrhea, bloody diarrhea, and colitis (including pseudomembranous colitis) have been reported with the use of topical clindamycin. Dosage Form: gel. Let us know what you think about the product. In Study 1, a total of 1252 patients were enrolled, and in Study 2, a total of 1288 patients were enrolled. Stool cultures for Clostridium difficile and stool assay for C. difficile toxin may be helpful diagnostically. Clindamycin phosphate is a water-soluble ester of the semi-synthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent antibiotic lincomycin. and tretinoin 0.025%) Gel, FOR TOPICAL USE ONLY Add the contents of the vial in the Lifting Pack, mix thoroughly using the brush for 20-30 seconds. Medically reviewed by Drugs.com. Sun Care contains a range of highly protective and moisturising components such as panthenol, allantoin, urea and serine that … Ziana Gel should be kept away from the eyes, the mouth, angles of the nose, and mucous membranes.Ziana Gel is not for oral, ophthalmic, or intravaginal use. Thank you for your patience! A sparkling wine Sangria in the bar patio while enjoying the breathtaking view is a bucket list moment!!!! New ... We are working on new features to make your experience with Viana … P. acnes resistance to clindamycin has been documented. Systemic absorption of clindamycin has been demonstrated following topical use of this product. This leaflet summarizes the most important information about Ziana Gel. Extractions are performed, followed by a specialized masque, moisturizer, and sunscreen. And, be the first to know about our promotions and special discounts. Read more about, Placenta Extract 5%, W&W Care & Sun protection SPF50+/PA+++, Your password must be at least 8 characters (only letters and numbers), what others have to say about working with us, Private Labeling opportunities in South Korea, Medi Cell Post-Treatment Sheet Mask (10ea), Callus Culture Extract: Firming and moisturizing, Centella asiatica extract: Soothing and moisturizing, Vitamin B5: Moisturizing and anti-acne effects. Ziana Gel may cause irritation such as erythema, scaling, itching, burning, or stinging. In an open-label, multiple-dose study treating 12 subjects with moderate to severe acne, the percutaneous absorption of tretinoin following 14 consecutive daily applications of approximately 4 g of Ziana Gel was minimal. However, orally and parenterally administered clindamycin has been reported to appear in breast milk. Island wide Delivery . Clindamycin binds to the 50S ribosomal subunits of susceptible bacteria and prevents elongation of peptide chains by interfering with peptidyl transfer, thereby suppressing bacterial protein synthesis. 9:57. Viana Hair Thickening & Volumizing Shampoo 275ml-CSNC3703. IMPORTANT: Not for mouth, eye, or vaginal use. In two independent studies with long-term topical application of tretinoin in mice, carcinogenicity was not observed. Analysis over the 12-week period demonstrated that cutaneous irritation scores for erythema, scaling, itching, burning, and stinging peaked at 2 weeks of therapy, and were slightly higher for the Ziana-treated group, decreasing thereafter. It may take some time for you to see improvement of your acne with Ziana Gel. In the event a patient treated with Ziana Gel experiences severe diarrhea or gastrointestinal discomfort, Ziana Gel should be discontinued and a physician should be contacted. The structural formula for tretinoin is represented below: Molecular Formula: C20H28O2 Molecular Weight: 300.44. Official website for Viana Cosmetics products. In both studies, tretinoin was administered topically (0.025% or 0.1%) three times per week for up to 2 years. U.S. Patent 6,387,383. Online Card Payments & Cash … Ziana Gel is not for oral, ophthalmic, or intravaginal use. Sinhala SRI LANKAN MAKE UP LOOK ... සිංහල: Soothing Night Time Cream Tutorial | Viana beauteEnhance My Fairness Night Cream - Duration: 2:12. Ziana Gel, a combination of a lincosamide antibiotic and a retinoid, contains clindamycin phosphate 1.2% and tretinoin 0.025%, formulated as a topical gel. The significance of these spontaneous reports in terms of risk to the fetus is not known. Our Viana Youth Dark Circle eraser is the best solution for dark circles, puffiness, wrinkles and fine lines. Inflammatory Lesion Count (% reduction from baseline), Non-inflammatory Lesion Count (% reduction from baseline), Total Lesion Count (% reduction from baseline). Clinical studies of Ziana Gel did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. (clindamycin phosphate 1.2% and tretinoin 0.025%) Gel. It works perfectly on irritated and very dry skin, giving the skin the necessary hydration and suppleness. Exposure to sunlight, including sunlamps, should be avoided during the use of Ziana Gel, and patients with sunburn should be advised not to use the product until fully recovered because of heightened susceptibility to sunlight as a result of the use of tretinoin. It is a very simple skin peeling in everyday life. Available for Android and iOS devices. At bedtime, squeeze a pea-sized amount of medication onto one fingertip, dot onto the chin, cheeks, nose, and forehead, then gently rub over the entire face. Health & Beauty, Night Creams, Other Products, Women's Health and Beauty Swabha Ceylon Night Cream Acne & Brightening 25g-CWNC3720 Health & Beauty , Night Creams , Other Products , Women's Health … The combined results are presented in Table 3. Viana Products Viana, a European-based company, has a delicious selection of veggie meats and spreads. Since 1974, Longust Distributing, Inc. has been a major wholesale flooring distributor servicing the Southwestern United States. Cutaneous safety and tolerance evaluations were conducted at each study visit in all of the clinical trials by assessment of erythema, scaling, itching, burning, and stinging: At each study visit, application site reactions on a scale of 0 (none), 1 (mild), 2 (moderate), and 3 (severe), and the mean scores were calculated for each of the local skin reactions. Because clinical trials are conducted under prescribed conditions, adverse reaction rates observed in the clinical trial may not reflect the rates observed in practice. Tretinoin has been shown to enhance photo co-carcinogenicity in properly performed specific studies, employing concurrent or intercurrent exposure to the drug and UV radiation. Ziana Gel should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Clindamycin has been shown to have in vitro activity against Propionibacterium acnes, an organism which has been associated with acne vulgaris; however, the clinical significance of this activity against P. acnes was not examined in clinical trials with Ziana Gel. Thinking about launching your own beauty product? Thank you for your patience! Filter All Bratwurst Burgers & steaks Chicken Chickin Cold pack Faux meat Fillets Frankfurters Greek Gyro High protein Hot dogs Kids Meal Misc meat Non-gmo Nuggets Organic Paleo Sausage Seitan Smoked Snack Spicy Steak Summer Tofu Vegan Viana Each gram of Ziana Gel contains, as dispensed, 10 mg (1%) clindamycin as phosphate, and 0.25 mg (0.025%) tretinoin in an aqueous-based gel. Thirty cases of temporally associated congenital malformations have been reported during two decades of clinical use of another formulation of topical tretinoin. [See Clinical Studies (14).]. Antiperistaltic agents such as opiates and diphenoxylate with atropine may prolong and/or worsen severe colitis. Studies indicate a toxin(s) produced by clostridia is one primary cause of antibiotic-associated colitis. Clindamycin has been shown to have neuromuscular blocking properties that may enhance the action of other neuromuscular blocking agents. Ziana (clindamycin phosphate 1.2% and tretinoin 0.025%) Gel is an antibiotic and retinoid combination gel product with two active ingredients. Ziana® (ZEE-AH-NA) Studies 1 and 2 were of identical design, and compared Ziana Gel to clindamycin in the vehicle gel, tretinoin in the vehicle gel, and the vehicle gel alone. We are working on new features to make your experience with Viana Care more convenient. Ziana is a trademark of Valeant Pharmaceuticals International, Inc. or its affiliates. Open the Multi EX-Lifting Polymer with the safety cap. For thorough protection against UV rays, apply every 3-4 hours. Add to cart. Ask your doctor or pharmacist for more information. Select one or more newsletters to continue. Clinical trials of Ziana Gel included patients 12–17 years of age. Find the latest offers and read customer reviews. By: Fertility (Segment 1) studies in rats treated orally with up to 300 mg/kg/day of clindamycin (approximately 290 times the amount of clindamycin delivered from the recommended clinical dose for Ziana Gel, based on body surface area comparison) revealed no effects on fertility or mating ability. Please enter your email below, and we’ll send you a new one. A local attraction - Placa Reial, that is situated near this bar, is a part of the original culture of the city. NOT FOR OPHTHALMIC, ORAL, Many ways to pay. excessive exposure to the sun, cold, and wind. As with Studies 1 and 2, the co-primary endpoints were mean percent reduction in lesion counts (inflammatory, non-inflammatory and total) and the EGS score. Severe colitis may result in death. After the basic skincare, apply a suitable amount on the face and other areas exposed to the sun. Please note that in order to be eligible for free shipping, you order amount should exceed $500 AFTER the promo code is applied. Adverse reactions that were reported in ≥1% of patients treated with Ziana Gel were compared to adverse reactions in patients treated with clindamycin phosphate 1.2% in vehicle gel, tretinoin 0.025% in vehicle gel, and the vehicle gel alone: NOTE: Formulations used in all treatment arms were in the Ziana vehicle gel. Patients with mild, moderate, or severe acne were enrolled in the studies. The plasma concentrations of the key tretinoin metabolites, 13-cis-retinoic acid and 4-oxo-13-cis-retinoic acid, ranged from 1.0 to 1.4 ng/mL and from 1.6 to 6.5 ng/mL, respectively. Quantifiable tretinoin plasma concentrations ranged from 1.0 to 1.6 ng/mL, with unquantifiable plasma concentrations in 50% to 92% of subjects at any given timepoint following administration. You can also ask your pharmacist or doctor for information about Ziana Gel that is written for healthcare professionals. It is not known whether clindamycin is excreted in human milk following use of Ziana Gel. CALL US NOW 077 055 6666. Ziana Gel was tested for maternal and developmental toxicity in New Zealand White Rabbits with topical doses of 60, 180 and 600 mg/kg/day. It … Enriched with the World’s most trusted Anti Aging Peptides and Natural Actives. Viana Signature Facial Deep cleansing, exfoliation, massage, and steaming loosen congestion and prepare your skin for a relaxing massage. This leaflet does not take the place of talking with your doctor about your acne or treatment. At bedtime, squeeze a pea-sized amount of medication onto one fingertip, dot onto the chin, cheeks, nose, and forehead, then gently rub over the entire face. Private Labeling opportunities in South Korea. Overview. It is important to look for a better sunscreen lotion with a higher Sun Protection Factor (commonly known as SPF) to save your skin from the most common sun … Next, remove pastry cream from fridge and spread throughout tart crust to form an even layer (if you chose not to use the chocolate ganache, this cream … In vitro studies have shown antagonism between these two antimicrobials. The safety and efficacy of once daily use of Ziana Gel for treatment of acne vulgaris were assessed in three 12-week prospective, multi-center, randomized, blinded studies in patients 12 years and older. For purposes of comparisons of the animal exposure to human exposure, the recommended human topical clinical dose is defined as 1 g of Ziana Gel applied daily to a 60 kg person. In Study 3, success on the EGS score was assessed by the percentage of subjects who had at least 2 grades of improvement from Baseline to Week 12. Via Natural Ultra Care Coconut Oil 1.5 oz - Via Natural Ultra Care Coconut Oil 1.5 oz Coconut Oil Concentrated Natural Oil Helps strengthen hair to prevent brittleness and breakage. Viana is recommended for the International cuisine served. Molecular Formula: C18H34ClN2O8PS Molecular Weight: 504.97. Ziana Gel contains the following inactive ingredients: butylated hydroxytoluene NF, carbomer 981 NF, citric acid USP, edetate disodium USP, glycerin USP, methylparaben NF, polysorbate 80 NF, propylparaben NF, purified water USP and tromethamine USP. Please leave your contact details below and we’ll get back to you shortly. if you are pregnant or planning to become pregnant. This combination medication is used to treat acne. Delay in Shipping - Due to seasonal activities (Christmas etc.) Make sure to subscribe to our newsletter to be the first to know about upcoming promotions. 4X 23G needles $ 77.00 to your needs you to See improvement of acne... 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